Apoptosis Reagents and Kits
Selleck Chemical LLC GSK2656157 50mg 1337532-29-2
GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases. GSK2656157 decreases apoptosis and inhibits excessive autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC LDC000067 10mg 1073485-20-7 LDC067
LDC000067 (LDC067) is a highly selective CDK9 inhibitor with IC50 of 44 nM, 55/125/210/ >227/ >227-fold selectivity over CDK2/1/4/6/7. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Biotium Mitochondrial MarkerMTC754 CF488A conjugate 0.1mgmL
Mitochondrial MarkerMTC754 CF488A conjugate 0.1mgmL
Biotium Mitochondrial MarkerMTC719 CF488A conjugate 0.1mgmL
Mitochondrial MarkerMTC719 CF488A conjugate 0.1mgmL
Abcam Human HRAS Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human HRAS Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human HRAS.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000593271 CASPASE ACTIVATED DNASE ELISA
Abcam Human SMAD2 knockout HeLa cell lysate.
Human SMAD2 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human WNT5A knockout HeLa cell lysate.
Human WNT5A knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HSPB8 (Hsp22) knockout HeLa cell lysate.
Human HSPB8 (Hsp22) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Bioymifi 5mg 1420071-30-2
Bioymifi, a small-molecule death receptor 5 (DR5) agonist, binds to the extracellular domain(ECD) of DR5 with a Kd of 1.2 ?M but showed little binding affinity to the DR4 ECD. It induces DR5 clustering and aggregation, leading to apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC A-1155463 1235034-55-5 5mg
A-1155463 (CAS 1235034-55-5) is a potent and selective small-molecule inhibitor of the anti-apoptotic protein BCL-XL exhibiting a Ki of 19 nM Developed through NMR fragment screening and structure-guided optimization A-1155463 demonstrates higher efficacy against BCL-XL-dependent cell lines compared to earlier inhibitors such as WEHI-539 In murine models administration of A-1155463 induces transient thrombocytopenia and inhibits the growth of BCL-XL-dependent H146 xenograft tumors supporting its utility for mechanistic studies on BCL-XL in tumor cell survival and therapeutic resistance The compound remains in preclinical research stages